The Emperor of All Maladies: A Biography of Cancer is as heart-wrenching as you’d expect from a book about a deadly disease, but it is also a majestically hopeful story because of its descriptions of the great strides in treatment. Practicing oncologist and researcher, Siddhartha Mukherjee, covers the vast sweeping history of cancer and its treatment, while focusing on a huge range of real people who played a role in cancer’s study, research and burgeoning cures. He always comes back to real individuals with cancer whom he has treated or studied and how their own struggles with their own disease are impacted by improvements in treatment. This is definitely a book about a disease but Siddhartha Mukherjee comes across as a deeply humane man writing a deeply humane book.
The earliest mention of cancer that the book talks about is a quote from scroll written by the Ancient Egyptian physician Imhotep over 4000 thousand years ago. The scroll gives a perfect description of breast cancer, but unfortunately for breast cancer sufferers from that time up until recently Imhotep concluded that there was nothing that could be done to help. Two centuries ago the standard treatment became a mastectomy without an anesthetic which is horrible to even contemplate. Today a range of options including surgery, chemotherapy and radiation mean a much higher survival rate.
Siddhartha Mukherjee points out that cancer is actually more than one disease and survival rates for some forms of the disease have improved rapidly, while others haven’t changed much. One joyful and astonishing story is the treatment of some common forms of childhood leukemia which went from a 5-year survival rate of less than 10% in the 1960s to a 5-year survival rate of over 90% today.
The Emperor of All Maladies is very readable and extremely compelling. It won the Pulitzer Prize for non fiction in 2011. Unless you are an oncologist be prepared to learn a lot from this 500-page epic of human ingenuity in overcoming a horrible disease that has caused untold suffering. I learned some astonishing facts, for instance that a chemical similar to mustard gas, the World War I trench horror, is used in chemotherapy.
As you’d expect from a reliable scientific book, The Emperor of All Maladies includes extensive notes with references, a glossary and an index. It also has some black and white photographs and drawings of notable people, events and procedures in the fight against cancer. The Emperor of All Maladies is a good choice if you like Oliver Sacks for his deep compassion for the people he treats and his profound knowledge of his area of expertise.
Check the WRL catalog for The Emperor of All Maladies.